User Guide / Getting Started with Rapid Screen

Getting Started with Rapid Screen

Welcome!

Welcome to the Scivera community and to your SciveraLENS Rapid Screen account!  Rapid Screen helps you manage your product and process chemical screening all in one place, providing you valuable list screening and hazard assessment information conducted by our team of board-certified toxicologists in a simple, fast and cost-effective way. This information allows you to make confident decisions quickly.

It also simplifies your processes – no more spreadsheet management of manual list checking allowing you to make confident decisions quickly.

This guide will walk you through a quick introduction to your Rapid Screen account and get you familiar with the different sections of Rapid Screen. We have other articles in this User Guide that can provide you with additional information about each section as well as an FAQ guide. Don’t forget, you can always reach out to us at support@scivera.com should you have any questions.

Let’s get started!

Overview:

Once you’ve set up your account and entered the Rapid Screen system, you’ll see an Overview page of Rapid Screen. This page is your own personal SciveraLENS dashboard that will change and update as you use the system.

Your dashboard will look different depending on your level of subscription. If you have one of our paid RS subscriptions, the CASRNs tile is a great place to keep an eye on the number of unique CASRNs you have entered into your account and help you monitor how close you are to your CASRN limit.

Collections:

Collections is where you will go to manage your “Collections” of chemicals. Collection is the term we use to describe any group of chemicals of interest to you. A Collection can be a formulation like a paint recipe or a textile auxiliary product. Or a Collection can be a list of chemicals within the same functional class (e.g. solvents). A Collection can also be a list of chemicals that are related only because they are of interest to you, your team, or even your customers. The point is, if you’d like to keep track of a chemical or chemicals, you can create a Collection to do just that. Collections is where you’ll be doing the majority of your work in Rapid Screen.

To add a new Collection, click on the little green plus (+) button on your Collections page. This will take you to the Collection Builder Wizard, which offers five different workflows you can choose from to assist you in building your collection.

To create a Collection with new CASRNs, you can choose from one of the first four workflows:

    • Quick Collection
    • BOS Builder
    • Upload BOS
    • Upload SDS

You can also create a Collection by using the Collection Assembler to link existing Collections (for example formulations you have already created a Collection for) and/or requesting data from others to complete your assessment (for example a mixture that you purchase from a sub-supplier).

As you go through the process of adding your collections, the Rapid Screen system will provide you with helpful tips along the way.  

 

Reviewing your Collection and Assessment Results:

Once we’ve processed your Collection, you’ll notice it will be listed on your Collections index page. Each Collection will have one or two symbols next to it depending on the plan you’ve purchased. The first symbol (a colored triangle) indicates if any chemicals from your selected lists are present in the Collection. If you are using one of the Tracker + Insight plans, you’ll see a second symbol next to each Collection. This symbol is a summary indication of the currently known human and environmental health attributes of the chemicals in the collection across 23 toxicological endpoints. You can tag and filter your Collections from this page for easier sorting and viewing. 

Try clicking on the name of your collection. Here you’ll see the Collection Detail view, which presents all chemicals in the collection in a table and flags the specific chemical(s) that are present on your List(s) of interest.

In a Tracker + Insight plan, you’ll also see a very detailed matrix of these 23 endpoints for each chemical and what Scivera’s toxicologists have currently been able to conclude about each. Hovering your pointer over each light will reveal a statement about each endpoint for each chemical. Clicking on each light will present the underlying references supporting our team’s assessment decision.

We’ve included a legend in the User Guide so you can remember what each light color indicates.

As you add more Collections, you’ll be able to manage and filter them on the Collections index page.

Lists:

Clicking on the Lists sidebar item will present to you with the lists and sublists that our team manages for your use in screening. Any or all are available to track when creating a Collection. You can mark your “favorite” lists or lists you refer to regularly. Lists that are marked will appear at the top of your Assign Lists screen when creating Collections for easy access and reference. 

Alerts:

The Alerts section is where SciveraLENS will keep you apprised of any updates to your chemicals of interest related to changes in lists or underlying human/environmental health characteristics. If a change occurs to a list that affects one of your collections, SciveraLENS Rapid Screen will generate an alert on the Alerts page. This way, you’ll be able to quickly see any impacts to your collections and chemicals of interest and be able to respond immediately since the system has done the work for you!

You can sort your Alerts by using the filter option in the top right of your screen. If this page is blank, you don’t have any alerts yet.

Managing Your Account:

In the top right of your screen, you’ll see your user name and icon. From here, you’ll be able to edit your profile, manage your account settings and billing profile, and logout.

Getting Started

Whether you signed up for our free trial of Rapid Screen or are just getting started with your new Rapid Screen account, here are some basic ways to get started.

Navigating your Collection index page

Your Collection Index page shows you all of the Collections that have been added to your Rapid Screen account. You can access your assessment results for your Collections directly from this page as well as manage your Collections. 

Sample Collections

When you log in to Rapid Screen for the first time, you’ll notice that you have two free sample Collections set up for you in your Collections window.

  • Sample Collection – PG vs. EG compare
  • Sample Collection 2 – Solvent compare

These Collections provide an example of different ways you can set up your own Collections when you’re ready to use Rapid Screen. Click on each of the links on the summary line to view the different reports available. Click on the:

  • Triangle for a report on List Hits by CASRN
  • Circle, Collection name or CASRNs for an Insight report showing you individual assessments for 22 human and environmental health endpoints and a report on List Hits by CASRN
  • Date under Last Alert to see any alert messages associated with that particular Collection
  • Alert Count for your Collection’s alerts listed by type and date
  • List Hits to view CASRNs by List
  • 3 dots to the far right of the summary line to:
    • View your Collection report
    • Manage your Collection
    • Download a CSV or Bill of Substances for the CASRNs in your Collection
    • Share your assessment results with others with redaction (redact the CASRNs and chemical names upon sharing) or in full disclosure mode
    • Archive a Collection. You can view your archived Collections by using the filter on your Collections page
    • Tag your Collection. You can then filter on these tags for easy sorting and searching

 

Getting the Most your of your Free Trial: Adding new Collections

As part of the Rapid Screen free trial, we’ve included 6 sample chemicals that have been pre-loaded to help give you a feel for the functionality of the system. Below are some example Collections using the 6 pre-loaded chemicals that you can add to the system in order to test out each of the four Collection creation methods. You also have the ability to add up to 5 additional unique CASRNs to test out Rapid Screen.

Rapid Screen organizes your chemicals of interest into Collections. A Collection of chemicals can be a single chemical, or a list of chemicals. Your list of chemicals can be a formulation for a product, or it could be a list of chemicals that you would like to compare for use in a specific application. Collections can be chemicals organized for any purpose. The way you organize your Collections is only limited by your imagination or chemicals management needs.

Create Collections in Rapid Screen using one of five different methods: (The CASRNs included in these examples will not count against your CASRN count in Rapid Screen.)

  1. Create a Quick Collection*
    1. Add a Collection name
    2. Type or copy and paste your chemicals into the CASRNs field
      1. Here are some CASRNs you can enter into the CASRNs field (make sure you’re just copying or entering the CASRN from the list below):
        1. 7732-18-5
        2. 5131-66-8
        3. 111-77-3
    3. Import existing Collections or request data from others if needed
    4. Add supporting documents if needed
    5. Assign the Regulated, Screening, or Preferred Chemical Lists against which you’d like to review/track your Collection
  2. Use the 5-step “BOS Builder” web wizard*
    1. Name your Collection
    2. Add chemicals of interest by name or CASRN (Chemical Abstract Service Registry Number) and concentration
      1. Here is a list of 3 chemicals to use in the BOS Builder web wizard to create a Collection using this method: (These CASRNs will not count against your CASRN limit in Rapid Screen)
        1. Water [CASRN: 7732-18-5] 75% (use decimal value of 0.75 for concentration)
        2. 1-butoxypropan-2-ol [CASRN: 5131-66-8] 20% (aka 0.2)
        3. 2-(2-methoxyethoxy)ethanol [CASRN: 111-77-3] 5% (aka 0.05)
    3. Import existing Collections or request data from others if needed
    4. Add supporting documents if needed
    5. Assign the Regulated, Screening, or Preferred Chemical Lists against which you’d like to review/track your Collection. By the way, BOS is an acronym for “bill of substances.” A BOS is a data document, similar to the long used term, BOM, (bill of materials) but with the additional information of specific chemicals that make up each material.
  3. Upload a Bill of Substances (BOS)*. You can create a BOS file in the form of a spreadsheet and upload it to your Rapid Screen account for screening a tracking. There is a specific format for the data (i.e., basic fields, etc) needed for a successful upload. You can find a template of this format here. This approach can be very useful for large Collections or for pulling data from an existing data resource. Feel free to check with our Support Team if you’d like to discuss bulk data import from an existing system to your Rapid Screen account.
  4. Upload a Safety Data Sheet (SDS)*. Start your Collection by uploading a text-based PDF of your Safety Data Sheet. Rapid Screen will pull out the relevant information from the SDS to create your Collection. As part of this process, you will also have the option to import existing Collections or request data from others and add supporting documents if needed.
  5. Use the Collection Assembler* to combine existing Collections into a new Collection. After filling in the basic information including Collection Name, you can import existing Collections from your own Rapid Screen account or request data from another Rapid Screen user. Then add supporting documents if needed and assign lists.

*To learn more about the different Collection Builder options in Rapid Screen, check out the specific User Guide article for each.

Ready to add a Collection?

To create a Collection using one of the above methods, click on “My Collections” in the navigation menu on the left side of your Rapid Screen app window (see red circle in image below).

Then click on the green circle with a “+” symbol in the upper right of the window.

It will take you to the Collection Builder Wizard, which offers five different methods you can choose from to assist you in building your Collection.

Give it a try. Send us a note if you have any trouble creating a Collection or check out the specific User Guide articles for each of the five Collection creation options.

 

Review screening results for each Collection (or how to get answers to your chemicals management questions, instantly)

When in the Collections page, you will see your current list of Collections. Each Collection will include two symbols to the left of the Collection name. The triangle symbol shows the result of the List Screen completed for the chemicals in each Collection.

Triangles:

The triangular symbol indicates whether or not there were any list “hits” for the chemicals in your Collection.

(Note – If you don’t put a concentration in for your chemicals (for example, when using Quick Collection), we assume 100% concentration for a chemical if not otherwise indicated.)

Circles:

The circular symbol (aka “traffic light”) is the instant result of the Human and Environmental Health Screen for the chemicals in the Collection. 

   Green is good. Green lights signal an overall assessment for a chemical or a specific human or environmental health endpoint shows evidence of low hazard. The Green/Gray light means Low Hazard based on limited evidence only (e.g., modeling, QSAR, etc.).

Yellow is acceptable. Yellow lights signal an overall assessment for a chemical or a specific human or environmental health endpoint shows evidence of moderate hazard. The Yellow/Gray light means Moderate Hazard based on limited evidence only (e.g., modeling, QSAR, etc.).

  Red indicates concern. Red lights signal an overall assessment for a chemical or a specific human or environmental health endpoint shows evidence of high hazard. The Red/Gray light means High Hazard based on limited evidence only (e.g., modeling, QSAR, etc.).

 Black indicates high concern. Black lights signal an overall assessment for a chemical or a specific human or environmental health endpoint shows evidence of high hazard. The Black/Gray light means Very High Hazard based on limited evidence only (e.g., modeling, QSAR, etc.).

Light blue indicates potential, but with caution. Light blue signals the endpoint does not show concern for the designated endpoint based on list evidence only but we have not yet completed a comprehensive hazard assessment on that particular chemical or endpoint. 

The light blue and gray light indicates an endpoint or chemical overall that does not show list evidence of concern, but after additional work by our toxicology team, we are not currently able to conclude an assessment. Data are currently not sufficient for an assessment.

The “MH” or Maximum Hazard result is based on the highest hazard assessment across all chemicals in the Collection and across all Human Endpoints and a combination of Environmental Health Endpoints for each chemical.

The “HC” or Hazard Category Score is based on an algorithm very similar to EPA Safer Choice, etc. that uses Core Endpoints (CMRD/PBT) and Supplemental Endpoints (all the rest) and suggests a Replace (Red Light), Concern (Yellow Light), Acceptable (Yellow/Green), Preferred (Green), or Incomplete (Gray)